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Compare care options for Obsessive-Compulsive Disorder

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What we found

Each option is for Obsessive-Compulsive Disorder. Research and local care are different facts.

Exposure and response prevention therapy (ERP)

What it is

Exposure and response prevention (ERP) is a form of CBT that NICE includes among treatment options for adults with OCD, within the scope of its guideline recommendation.

Official guideline documents · checked Aug 24, 2026

Relationship: supports

Statement scope

Document

CG31

Jurisdiction

United Kingdom

Population

adults with OCD

Source collection coverage: global

Pointer: /document/recommendation

Source: Official guideline documents. Checked Aug 24, 2026. Scope: global.

Why it is on this page

People: niños y adolescentes con TOC

GuíaSalud GPC 634: TOC en niños y adolescentes · checked Oct 16, 2026

Relationship: recomendado para población pediátrica con TOC

Statement scope

Jurisdiction

Sistema Nacional de Salud de España

Population

niños y adolescentes con TOC

Source collection coverage: country:ES

Pointer: /recommendations/0

Open source

Source: GuíaSalud GPC 634: TOC en niños y adolescentes. Checked Oct 16, 2026. Scope: country:ES. Link: https://portal.guiasalud.es/wp-content/uploads/2025/02/gpc_634_toc_nino_adolescente_compl.pdf

Why it is on this page

People: adults with OCD

Official guideline documents · checked Aug 24, 2026

Relationship: guideline recommendation

Statement scope

Document

CG31

Jurisdiction

United Kingdom

Population

adults with OCD

Source collection coverage: global

Pointer: /document/recommendation

Source: Official guideline documents. Checked Aug 24, 2026. Scope: global.

Research for Obsessive-Compulsive Disorder

Research suggests benefit in this exact scope

Published Oct 7, 2026 · revision 4

What research says

NICE CG31, recommendation 1.5.1.1, identifies psychological treatment that includes ERP as a low-intensity initial option for adults with OCD when impairment in everyday functioning is mild, when they prefer a low-intensity approach, or both. This is an attributed guideline recommendation for that adult group.

Official guideline documents · checked Oct 3, 2026

Relationship: supports the attributed adult initial-treatment recommendation and its delivery qualifiers

Statement scope

Formulation or format

brief individual cognitive behavioural therapy (CBT; including ERP) using structured self‑help materials; brief individual CBT (including ERP) by telephone; group CBT (including ERP)

Guideline

CG31

Indication

obsessive-compulsive disorder

Intensity

up to 10 therapist hours per patient; group CBT (including ERP) may exceed 10 hours

Treatment phase

initial treatment

Population

Adults with OCD whose functional impairment is mild and/or who prefer a low-intensity approach

Recommendation

1.5.1.1

Source collection coverage: global

Pointer: /document/recommendation

Open source

Source: Official guideline documents. Checked Oct 3, 2026. Scope: global. Link: https://www.nice.org.uk/guidance/cg31/chapter/Recommendations

Delivery and time commitment

For this initial-treatment pathway, NICE CG31 describes low-intensity care as using up to 10 hours of therapist time per patient. Its listed formats include brief individual CBT with ERP supported by structured self-help materials, brief individual CBT with ERP by telephone, and group CBT with ERP. In the group format, a patient may receive more than 10 hours of therapy.

Official guideline documents · checked Oct 3, 2026

Relationship: supports the attributed adult initial-treatment recommendation and its delivery qualifiers

Statement scope

Formulation or format

brief individual cognitive behavioural therapy (CBT; including ERP) using structured self‑help materials; brief individual CBT (including ERP) by telephone; group CBT (including ERP)

Guideline

CG31

Indication

obsessive-compulsive disorder

Intensity

up to 10 therapist hours per patient; group CBT (including ERP) may exceed 10 hours

Treatment phase

initial treatment

Population

Adults with OCD whose functional impairment is mild and/or who prefer a low-intensity approach

Recommendation

1.5.1.1

Source collection coverage: global

Pointer: /document/recommendation

Open source

Source: Official guideline documents. Checked Oct 3, 2026. Scope: global. Link: https://www.nice.org.uk/guidance/cg31/chapter/Recommendations

More intensive option

For adults with OCD whose day-to-day functioning is moderately impaired, England’s NICE guideline CG31 (recommendation 1.5.1.3) says they should be offered a choice between a course of an SSRI medicine and more intensive CBT that includes ERP, meaning more than 10 hours of therapist time, because the two appear to be comparably effective. This describes a guideline pathway; a local provider’s approach and an individual’s needs may differ.

Official guideline documents · checked Oct 7, 2026

Relationship: supports the attributed moderate-impairment choice and intensive therapist time

Statement scope

Alternative

a course of an SSRI

Delivery

more intensive CBT (including ERP; more than 10 therapist hours per patient)

Guideline

CG31

Indication

Obsessive-compulsive disorder

Population

Adults with OCD with moderate functional impairment covered by NICE CG31

Recommendation

1.5.1.3

Section

1.5.1 Initial treatment options: Adults

Source collection coverage: global

Pointer: /document/recommendation

Open source

Source: Official guideline documents. Checked Oct 7, 2026. Scope: global. Link: https://www.nice.org.uk/guidance/cg31/chapter/Recommendations

Severe impairment option

For adults with OCD whose day-to-day functioning is severely impaired, England’s NICE guideline CG31 (recommendation 1.5.1.4) says they should be offered combined treatment: an SSRI medicine together with CBT that includes ERP. This describes a guideline pathway; a local provider’s approach and an individual’s needs may differ.

Official guideline documents · checked Oct 7, 2026

Relationship: supports the attributed severe-impairment combined treatment

Statement scope

Delivery

combined treatment with an SSRI and CBT (including ERP)

Guideline

CG31

Indication

OCD

Population

Adults with OCD with severe functional impairment

Recommendation

1.5.1.4

Section

1.5.1 Initial treatment options: Adults

Source collection coverage: global

Pointer: /document/recommendation

Open source

Source: Official guideline documents. Checked Oct 7, 2026. Scope: global. Link: https://www.nice.org.uk/guidance/cg31/chapter/Recommendations

Children and young people

For children and young people with OCD whose functioning is moderately to severely impaired, or mildly impaired when guided self-help has not worked or was declined, NICE CG31 (recommendation 1.5.1.9) names CBT that includes ERP as the treatment of choice, involving the family or carers and adapted to the child’s developmental age. This describes a guideline pathway in England; a local provider’s approach and an individual’s needs may differ.

Official guideline documents · checked Oct 7, 2026

Relationship: supports the attributed young-people treatment of choice and its family and age adaptations

Statement scope

Delivery

CBT (including ERP) that involves the family or carers and is adapted to suit the developmental age of the child

Format

Group or individual formats depending upon the preference of the child or young person and their family or carers

Guideline

CG31

Indication

OCD

Issuer

National Institute for Health and Care Excellence

Population

Children and young people with OCD with moderate to severe functional impairment, and those with OCD with mild functional impairment for whom guided self-help has been ineffective or refused

Recommendation

1.5.1.9

Section

1.5.1 Initial treatment options: Children and young people

Source collection coverage: global

Pointer: /document/recommendation

Open source

Source: Official guideline documents. Checked Oct 7, 2026. Scope: global. Link: https://www.nice.org.uk/guidance/cg31/chapter/Recommendations

Compared with the others: Not directly compared. We show each option’s own research.

Sertraline

What it is

We have not added a short description yet.

Why it is on this page

People: patients with obsessive-compulsive disorder as labeled

DailyMed sertraline (Zoloft) label · checked Oct 16, 2026

Relationship: labeled indication

Statement scope

Formulation or format

tablet, film coated; oral solution

Indication

obsessive-compulsive disorder

Population

patients with obsessive-compulsive disorder as labeled

Section code

34067-9

Source collection coverage: country:US

Pointer: /sections/1

Open source

Source: DailyMed sertraline (Zoloft) label. Checked Oct 16, 2026. Scope: country:US. Link: https://dailymed.nlm.nih.gov/dailymed/services/v2/spls/fda754f6-d0f3-4dce-a17a-927d64f912f7.xml

Research for Obsessive-Compulsive Disorder

Not reviewed

No current published assessment exists for this exact Treatment and Need. This does not establish benefit or no benefit.

Compared with the others: Not directly compared. We show each option’s own research.

Page link: https://everyoption.org/compare/ocd?treatments=erp%2Csertraline&locale=en-US